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14.30-14.45
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Welcome
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Session I
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NON CODING RNA
Chair: Valerio Orlando
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14.45-15.30
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Keynote Lecture: Ruggero De Maria
From biomarkers to biotherapeutics: the new frontier of microRNAs in cancer
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15.30-15.55
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Luigi Naldini
Exploiting and antagonizing microRNA regulation in gene therapy
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15.55-16.15
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Coffee Break
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16.15-17.25
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Poster Session I
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17.25-17.50
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Stefano Volinia
Reprogramming of miRNA networks in cancer and leukemia
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17.50-18.15
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Claudio Schneider
The stromal microenviroment, its precursor cells and role in serous ovarian carcinoma
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18.15-18.30
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Silvia Barabino
Genotoxic stress modulates alternative pre-mRNA splicing by modifying the intracellular distribution of SRPK2
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18.30-18.45
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Maria Cristina Onorati
Functional interaction between chromatin remodelers and non-coding RNA’s
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Session II
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GENOMIC STABILITY, PLASTICITY AND DIFFERENTIATION
Chair: Giulia Piaggio
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9.00-9.45
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Keynote Lecture: Marco Foiani [Podcast sponsored by QIAGEN]
Mechanisms controlling genome integrity
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9.45-10.10
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Maria Pia Longhese
Regulating processing of accidental and specialized chromosome ends
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10.10-10.35
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Enrico Avvedimento
Transcription driven by oxidation: chromatin loops
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10.35-11.00
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Claudio Brancolini
Isopeptidases in the control of apoptosis: exploring new therapeutic potentials
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11.00-11.20
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Coffee Break
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11.20-11.35
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Chiara Lanzuolo
Maintenance of PcG mediated epigenetic signatures through S phase in Drosophila melanogaster
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11.35-11.50
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Elena Longobardi
Expression and function of the TALE proteins in mouse mammary gland stem cell and progenitors
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11.50-12.05
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Simona Pilotto
Design and development of new inhibitors of the histone demethylases LSD1 and LSD2
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Session III
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SIGNALING PATHWAYS
Chair: Giannino Del Sal
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12.05-12.50
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Keynote Lecture: Pier Paolo Di Fiore [Podcast sponsored by QIAGEN]
Decoding the endocytic matrix
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12.50-13.50
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Lunch
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13.50-14.15
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Alberto Gulino
Regulation of Hedgehog/Gli function in neural stem/progenitor and medulloblastoma cells
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14.15-14.40
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Francesca Granucci
CD14 regulates the dendritic cell life cycle through NFAT activation following LPS encounter
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14.40-14.55
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Barbara Stecca
Hedgehog-Gli signaling controls neural stem cell and tumor cell numbers
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14.55-15.10
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Fiamma Mantovani
BRD7 is a candidate tumor suppressor gene required for p53 function
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15.10-15.25
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Fabiana Aceto
Mechanism of retinoic acid-induced transcription: epigenetic changes, DNA oxidation and formation of chromatin loops
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15.25-16.35
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Poster Session II
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16.35-16.55
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Coffee break
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Session IV
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SIGNALING PATHWAYS AS THERAPEUTIC TARGETS
Chair: Francesco Cecconi
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16.55-17.40
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Keynote Lecture: Alberto Bardelli [Podcast sponsored by QIAGEN]
Cancer mutations and targeted therapies in cells, mice and patients
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17.40-18.05
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Giovanni Blandino
Therapeutic targets in breast cancer
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18.05-18.30
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Antonello Pietrangelo
Targeting the hepcidin signalling pathway to cure human iron disorders
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18.30-18.45
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Anna Montesano
Resveratrol promotes myogenesis and hypertrophy in murine myoblasts
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18.45-19.00
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Alessio Valletti
Identification of tumor-associated alternative splicing events in human cancer through EST-based computational prediction and experimental validation
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19.00-19.15
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Simona Pedrotti
The RNA-binding protein Sam68 regulates SMN2 exon 7 alternative splicing in spinal muscular atrophy
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20.30
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Social dinner
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Session V
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CELL BIOLOGY & CELL THERAPY
Chair: Enrico Avvedimento
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9.00-9.45
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Keynote Lecture: Rosario Rizzuto
Mitochondria, calcium, and cell death
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9.45-10.10
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Francesco Cecconi
Autophagy regulation in cell death and survival
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10.10-10.35
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Michele De Luca
Epithelial stem cells and regenerative medicine
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10.35-10.55
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Coffee Break
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10.55-11.20
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Luca Scorrano
Size matters: mitochondrial elongation is a conserved and protective step of autophagy
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11.20-11.35
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Paolo Grumati
Autophagy is defective in dystrophic muscle and its reactivation rescues myofiber degeneration
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11.35-11.50
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Marco Tripodi
Epithelial differentiation and liver zonation of hepatocyte imply coordinate activation and repression of HNF4α target genes
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11.50-12.55
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Chiara D'Onofrio "Giovani" Award
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12.55
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Final remarks
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