SIBBM Seminar
Frontiers in Molecular Biology
Programme
Thursday, 15 May
| 13.00-14.30 |
REGISTRATION |
| 14.30-14.45 |
Welcome to the participants and overview of the meeting |
| Session I |
The RNA revolution (Chair: Giuseppe Macino) |
| 14.45-15.45 |
Giuseppe Macino (RM) Small RNAs function as genome defence mechanism and key regulators of gene expression |
| 15.45-16.10 |
I. Bozzoni (RM) Regulatory circuitries controlled by microRNAs in myeloid differentiation |
| 16.10-16.30 |
Coffee Break |
| 16.30-17.40 |
Posters |
| 17.40-18.05 |
Stefano Piccolo (PD) MicroRNA control of Nodal signalling |
| 18.05-18.30 |
Roberto Gherzi (GE) Many faces of the RNA binding protein KSRP |
| 18.30-18.45 |
Francesco Talotta (NA) An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation |
| 18.45-19.00 |
Laura Fontana (RM) MicroRNAs 17-5p/20a/106a control monocytopoiesis through AML1 targeting and M-CSF receptor upmodulation |
| 19.00-19.15 |
Daphne S. Cabianca (MI) An RNA potentially regulating 4q35 gene expression in FSHD |
| 19.15-19.30 |
Giulia Solda’ (MI) A new class of non-coding RNAs associated with 3’ untranslated regions of mRNAs |
Friday, 16 May
| Session II |
The epigenome and gene regulation (Chair: Valerio Orlando) |
| 08.45-09.45 |
Valerio Orlando (NA) The role of the Epigenome in gene regulation |
| 09.45-10.10 |
Davide Corona (PA) The nucleosome remodeling ATPase ISWI is regulated by poly-ADP-ribosylation |
| 10.10-10.35 |
Andrea Mattevi (PV) Lysine-specific histone demethylase (LSD1): oxidative chemistry for chromatin remodelling |
| 10.35-11.00 |
Coffee Break |
| 11.00-11.25 |
Lucia Altucci (NA) Signalling of HDAC inhibitors in cancer and non-cancer diseases |
| 11.25-11.50 |
Nicoletta Landsberger (VA) Molecular genetics of Rett syndrome: when epigenetic signals go unrecognized |
| 11.50-12.05 |
Gaetano Gargiulo (MI) Genome-wide survey of chromatin accessibility and dynamics during hematopoietic stem and progenitors differentiation |
| 12.05-12.20 |
Massimiliano Gaetani (MI) The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression |
| 12.20-12.35 |
Giacomo Donati (MI) NF-Y, a transcriptional regulator with H2A-H2B structural and functional properties |
| 12.35-13.30 |
Lunch at the campus bar |
| 13.30-14.30 |
Free time for scientific discussions |
| Session III |
Mechanisms in transcriptional control (Chair: Giannino Del Sal) |
| 14.30-15.30 |
Giannino Del Sal (TS) Mechanisms in transcriptional control |
| 15.30-15.55 |
Alessandra Agresti (MI) Sustained oscillations of functional NF-κB encode optimal gene expression programs |
| 15.55-16.20 |
Giorgio Dieci (PR) Novel RNA polymerase III promoters and terminators in the human genome |
| 16.20-16.40 |
Coffee Break |
| 16.40-17.50 |
Posters |
| 17.50-18.15 |
Massimo Crippa (MI) Poised transcription factories prime silent uPA genes prior to activation |
| 18.15-18.40 |
Diego Di Bernardo (NA) A systems biology approach to study transcription factors in mammalian cells: an application to the TF p63 |
| 18.40-18.55 |
Giuseppina Lambazzi (NA) GFP-engineered embryonic stem cell lines as a tool for the identification of key regulators of cardiac and neural differentiation |
| 18.55-19.10 |
Alessio Zippo (SI) PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation |
| 19.10-19.25 |
Luca Giorgetti (MI) Clustering of transcription factor binding sites: Understanding the rationale behind a recurring genomic theme |
| 20.30 |
Social dinner at the restaurant Paradosso |
Saturday, 17 May
| Session IV |
Transcription, differentiation and disease (Chair: Pier Giuseppe Pelicci) |
| 08.45-09.45 |
Pier Giuseppe Pelicci (MI) Biological properties of cancer stem cells |
| 09.45-10.10 |
Flavio Leoni (MI) The anti-inflammatory profile of the histone deacetylase inhibitor ITF 2357 |
| 10.10-10.35 |
Antonio Bilancio (NA) Role of Pi3-kinase signalling in steroid action |
| 10.35-11.00 |
Coffee Break |
| 11.00-11.25 |
Pier Lorenzo Puri (RM) Signal-dependent control of epigenetic modifications during skeletal myogenesis |
| 11.25-11.40 |
Enza Lonardo (NA) Identification and characterization of cripto antagonists to improve the use of stem cell-based therapy in neurodegenerative disorders |
| 11.40-11.55 |
Nadia Lo Iacono (MI) Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in the EEC and SHFM congenital limb defects |
| 11.55-12.10 |
Beatrice Bodega (MI) Polycomb complex shapes the higher order of D4Z4 chromatin structure during differentiation of normal and FSHD muscle stem cells |
| 12.10-13.00 |
Chiara D'Onofrio 'Giovani' Award Final remarks |